A Genetically Engineered Cell Line Resistant to Subgroup J Avian Leukosis Virus Infection (C/J)
نویسندگان
چکیده
منابع مشابه
Avian Leukosis Virus Subgroup J in Layer Chickens, China
To the Editor: In recent years, cases of avian leukosis virus subgroup J (ALV-J) infection and tumors in commercial layer chickens and breeders of egg-type chickens have been emerging in the People’s Republic of China. ALV-J was fi rst isolated from meattype chickens with myeloid leukosis in 1988. Although egg-type chickens have been experimentally infected with ALV-J to induce tumors (1), fi e...
متن کاملNonconserved tryptophan 38 of the cell surface receptor for subgroup J avian leukosis virus discriminates sensitive from resistant avian species.
Subgroup J avian leukosis virus (ALV-J) is unique among the avian sarcoma and leukosis viruses in using the multimembrane-spanning cell surface protein Na(+)/H(+) exchanger type 1 (NHE1) as a receptor. The precise localization of amino acids critical for NHE1 receptor activity is key in understanding the virus-receptor interaction and potential interference with virus entry. Because no resistan...
متن کاملgga-miR-375 Plays a Key Role in Tumorigenesis Post Subgroup J Avian Leukosis Virus Infection
Avian leukosis is a neoplastic disease caused in part by subgroup J avian leukosis virus J (ALV-J). Micro ribonucleic acids (miRNAs) play pivotal oncogenic and tumour-suppressor roles in tumour development and progression. However, little is known about the potential role of miRNAs in avian leukosis tumours. We have found a novel tumour-suppressor miRNA, gga-miR-375, associated with avian leuko...
متن کاملMetastatic cutaneous neuro- myofibroblastic sarcoma induced by avian leukosis virus subgroup J in a rooster (Gallus gallus domesticus)
An adult native cock (Gallus gallus domesticus) referred to the aviary clinic with multiple different sizes of round dermal nodules. The bird died few days later, and was then submitted for further evaluation. Macroscopic and microscopic examinations as well as a PCR test were done to identify type and cause of the tumor. In histopathological assessment of biopsy specimen, it consisted of inter...
متن کاملmolecular studies on avian leukosis virus subgroup j (alv-j) infections in grandparent flocks in iran
abstract: subgroup j avian leukosis virus (alv-j) was isolated in the late 1980s from meat-type chickens in the united kingdom. alv-j with exception of some acute variants, cause myeloid leukosis in meat-type chickens with long incubation period.in this study while the status of avian leukosis virus subgroup j in six different strain of broiler grandparent flocks of iran evaluated, the evaluati...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Virology
سال: 1999
ISSN: 0042-6822
DOI: 10.1006/viro.1999.9993